LATVIAN SCIENTISTS

Professor Dr.habil.med. Andris RUBINS

Professor Andris RUBINS Head of the Chair of  Dermatovenerology, Riga Stradins University 16 Dzirciema street, Riga, LV-1007 Latvia      Tel.: +371 7370395; mob.tel. 9481725      Fax.: +371 7370395      E-mail: [email protected]; [email protected] Director of Latvian Dermatology Institute,Ltd 14 Perses street , Riga, LV-1011, Latvia      Tel.: 7284575, 7287740 President of Latvian Association of Dermatovenerologists President of Baltic Association of Dermatovenerologists

Date and place of birth 

November 19,1947, Sigulda, Latvia

Interests

• Immunopathogenesis and immune therapy of skin diseases
• Approbation and introduction of new drugs in dermatology
• STDs epidemiology, prevention and therapy.

Languages

Latvian - native lg., English, Russian - fluent

Education, professional training

• 1968 – 1974 Riga Medical Institute.
• 1974- 1975 Internship in skin and venerological diseases in Riga, Republican dispensary of skin and venerological diseases.
• 1976- 1981 doctor-dermatovenerologists at Riga dispensary of skin and venerological diseases.
• 1981 – Defence of thesis for a scientific degree in medicine in Moscow.
• 1981- 1985 Head of research laboratory at Riga Medical Institute.
• 1982- 1984 Assistant at the Chair of Dermatovenerology at Riga Medical Institute.
• 1984 – 1988 Assistant professor at RMI Chair of Dermatovenerology.
• 1987 – Defence of theses for a degree of Doctor of Medical Sciences in Moscow „Immunopathogenesis and Immune Therapy of Psoriasis”.
• Since 1988 - Doctor of Medical Sciences.
• Since 1988 – Professor of Latvian Medical Academy.
• From 1991 – present Head of the Chair of Dermatovenerology.
• From 2001 – Dr.habil.med.

Current job, occupation

• Professor, dermatovenerologist, Riga Stradins University, Head of the Chair of dermatovenerology from 1991 – present.
• President of Latvian Association of Dermatovenerologists,since 1991- present
• President of Baltic Association of Dermatovenerologists, since1991 - present
• Member of Association Board of Central East Europe Dermatovenerologists, since 1997 - present
• Member of the scientific editorial board of the journal „Giorn.Internationale Dermatologica Ped.” (Italy) and the journal „Sexually Transmitted Diseases” and „Immunopathology, Allergology, Infectology”, (Moscow,Russia)
• Member of European Academy of Dermatovenerologists from 1991 – present.
• Member of New York Research Academy since 1993.
• Member of American Academy of Dermatovenerologists from 1998 – present.
• Member of the Board International Union Against Sexually Transmitted Infections- Europe, from 1997 - present
• Member of the Board (Internal Medicine) of Riga Stradins University from 1997 – present.
• Director of Latvian Dermatology Institute,Ltd from 2001 – present.

Professional certificate - Dermatovenerology

Research Activities

Author of more than 180 research publications. 5 inventions and patents, 4 monographs.

Honours and Awards

• Corresponding Member of Finnish Society of Dermatologists from 18.02.2000.
• Honorary Member of Rumania Society of Dermatologists from 2002.

• Bronze award of the Netherlands Society of Dermatovenerologists for the presentation at 8 EADV congress in Amsterdam in 1999.

Courses

• Dermatovenerology – for students and residents of Riga Stradins University, Latvia

1. Psoriasis, immunopathogenesis and immune therapy.
2. Immunopathogenesis and the latest developments in the therapy of skin diseases.
3. Epidemiology, diagnostics, differential diagnostics and therapy of sexually transmitted diseases.
4. Dermatovenerology in Latvia: advances and perspectives.

At the USA universities: Univ.of Michigan, Ann Arbor, NIH Bethesda, MD; Med.Univ. of South Carolina, Charleston,
Univ. of Texas, Galveston; Medic.Coll. of Wisconsin, Northwestern Univ, Chicago; New Jersey Med. School, NJ: New York Univ. at Stony Brook; Bowmann Gray School of. Med. Winston-Salem; Japan: Tokyo Univ. Kinki Univ., Osaka, Kyoto Univ.; Germany - Univ. of. Dusseldorf; Univ. of Munich; Univ.of Marburg, Univ. of Keel, Univ. of Koln, University of Erfurt

Reports delivered

• 20^th World Congress of Dermatology, Paris 1^st-5^th July 2002
• October 2-6, 2002, Prague, Czech Republic, 11 EADV congress
• November, 2002, Bucarest, Rumania Dermatovenerologists congress
• December, 2002 ,5^th Congress (ESSIR), Hamburg
• 4 Baltic Dermatovenerologists congress, 22-23 May,2003 Tallin, Estonia
• LDVA 15 congress, Riga, September12-13. 2003
• Russian 1 Dermatovenerologists congress SanktPetersburgh, Russia, September 23-26,2003
• October15-18,2003, 12^th EADV congress Barselona (Spain)
• German STD congress, Marburg , Germany, May 7-8, 2004
• LDVA 16 congress, Riga, September 10-11,2004

Starting with 1991, participation at all congresses of European Academy of Dermatovenerology (EADV), as well as World congresses in 1992,1997, 2002 and congresses organized in other countries (2000 - in Holland, 2001 – in Germany, 2001 – in Greece, 2002- in Romania, 2003 – in Russia).

Chairperson of 14th, 15th, 16th congresses of Latvian Association of Dermatovenerologists.

Organizing committee of BADV 1-4 congresses , chairman of 3rd congress.

Research projects

1. FG 506-08-07 “A multicentre, randomised, open label, observer blinded, parallel group study to assess efficacy and safety of Tacrolimus gel 0.3%, vs Calcipotriol ointment 0.005% vs Tacrolimus cream 0.5% in the treatment of mild to moderate plaque psoriasis” of company Fujisawa GmbH, Germany (2001- 2004).

2. FG-506-06-21 “A long-term open label, non-comparative study to evalute the safety of 0,1% Tacrolimus (FK506) ointment for treatment of atopic dermatitis “ (1998-2004) of company Fujisawa GmbH, Germany

3. FG – 506-06-33 “A long-term, non-comparative study to evaluate the safety and efficacy of Tacrolimus ointment in paediatric patients” (2004-2006) of company Fujisawa GmbH, Germany.

4.FG-506-06-32 “A randomised, multi-centre, double-blind, pharmacokinetic study of Tacrolimus ointment 0.03% in paediatric patients (aged 3 months to 24 months) with atopic dermatitis following first and repeated once daily or twice daily application of the Tacrolimus ointment” (2004-2006) of company Fujisawa GmbH, Germany.

Supervision of Doctoral Students

Two theses for the degree of Dr.med. have been defended under my guidance, two theses are to be defended, two are supervised.

Monographs

1. Illustrated Manual in Dermatovenerology , Rubins A., Gutmane R., Siegel D., Riga, 1996., 268 pp. In Latvian
2. A book „Sexually Transmitted Diseases” (A.Rubins, R.Gutmane, S.Rubins et al.) under profesor A.Rubin’s editing, Riga, 2001, 194 pp.
3. Illustrated Handbook in Dermatovenerology, Rubins A., Gutmane R., Siegel D., Riga, 1997, 292 pp. (in Russian)
4. A book „Skin Diseases and their Therapy“, (A.Rubins, R.Gutmane, S.Reitamo et al.)under profesor A. Rubin’s editing, LDF, Riga 2002. 

Research articles

1. Th. Ruzicka, Th. Bieber, Er. Schopf, A. Rubins et al, A short-term trial of Tacrolimus ointment for atopic dermatitis. The New England Journ. of Med. Vol.337, N 12, 1997, pp. 816-821.
2. M. Zonneveld, A. Rubins, Jablonska S. at al., Tacrolimus (FK506) is not effective in chronic plaque psoriasis. A pilot study.” Journal “Archives of Dermatology”, 1998; 134 (9): 1101-1102.
3. M. Zonneveld, A. Rubins, Jablonska S., Dobozy A., Ruzicka T., Kind P. et al. Erratum: topical tacrolimus is not effective in chronic plague psoriasis, Archives of Dermatology 1998; 134 (11): 1386-1386.
4. A.Rubins, R. Gutmane, S. Rubins et al, Epidemiology of syphilis in Latvia., J., Acta Dermatovenerologica A.P.A. Vol 8, 1999 nr.2, p. 59-62.
5. A.Rubins, A. Viksna, History Dermatovenerology in Latvia, CEEDVA Bulletin 1, 1999, p. 28- 34.
6. Rubins A.,Merson A., Subpopulations T-lymphocytes in psoriatic patients and their changes during immunotherapy. J.Amer.Acad.Derm.,1987,17:972-
7. Reitamo S.,Wollenberg A.,Schop, Cambazarol F., Marks R.,Ruzicka Th., Christopher E., Kapp A., Dubertret L., Rubins A., Jablonska St., Rustin M., Safety and Efficacy of 1 Year of Tacrolimus Ointment Monotherapy in Adults with Atopic Dermatitis, Amer.Medical Association, Arch.Dermatol. vol,136,2000., p.999-1006.
8. A.Rubins, S.Rubins, I.Jakobsone, L.Cigorevska, Syphilis – Theory and Practice in Latvia, Forum for Nordic dermatovenerology, No.4, vol.7, November 2002, p.12-19.
9. A.Rubins, J.Vetra, L.Ivanova, V.Shidlovska,Options available for the conservative therapy of feebly granulated foot and skin ulcers,Vest.Dermatol Venerol, 2003; 3: 43-45.
10. J.Harper, C.Smith, A.Rubins, et al.  A multicentre study of the pharmacokinetics of Tacrolimus ointment after first and repeated application to children with atopic dermatitis. - Journal of Investigative Dermatology, 2005,    124, pp. 695-699.
11. A.Rubins, R.Gutmane, N.Valdmane, P.Stevenson, N.Undre. Pharmacokinetics of 0,1% Tacrolimus ointment after first and repeated aplications to adults with moderate to severe Atopic Dermatitis. - Journal of Investigative Dermatology, 2005,   125, pp. 68-71.
12. J.Ortonne, P. Van de Kerkhof, A.Rubins et al., 0,3% Tacrolimus gel and 0,5% Tacrolimus cream show effifacy in the treatment of adults with mild to moderate plaque psoriasis: results of a randomised, open-label, observer blinder study. - Acta Dermato-Venerologica, 2006, 86, pp. 29-33.

Patents of the Republic of Latvia

1. Patent Nr.12448, A method of diagnostics of lower extremity skin trophic ulcers , Latvijas Republika, 20.07.2000.g. A. Rubins, L.Ivanova, R.Batova et al.
2. Patent Nr. 11528.20.08.1997, Anti-inflammatory, anti-analgesic drug for parenteral use and the method of its preparation. Inventors R.Batova, E.Petersone, A.Lazdins, V.Krilovs, A.Rubins.
3. Patent Nr.11594.2008.1997, Medical drug for psoriasis treatment. Inventors R.Batova, E.Petersone, A.Lazdins, V.Krilovs, I.Hartmane, A.Rubins.

        1998-2004: participation – 24, chairing 7

Last update 16.02.2007